ABOUT US
Under Development
Managed by a Professional Team Over 20 Years of Experience in Digital Biotechnology
R&D and Investment Funds Raised Towards Development & Commercialization of the World's First Mitochondrial Therapy
Our mission is to revolutionize healthcare
by harnessing the untapped potential of mitochondria.
We are committed to advancing mitochondria-based technologies to develop innovative therapies for rare, chronic, and hard-to-treat diseases—improving quality of life through science-driven breakthroughs.
OUR VALUES
We foster innovation to push the boundaries of biotechnology, embrace collaboration to work across disciplines and partners, harness advanced technology to solve unmet medical needs, and uphold rigor in every process to ensure excellence and trust.
These values are embedded in everything we do—every discovery, every trial, every breakthrough.
UNDERSTANDING
They not only generate energy but also play an important role in cell proliferation, signaling, etc.
Mitochondria have unique characteristics that can be delivered into cells through endocytosis. With PAEAN's mitochondria-based therapeutics, we transform mitochondria into powerful biopharmaceutical agents to address critical medical needs.
Applying the unique characteristics of mitochondria and proprietary technology platform, PAEAN is developing a first-in-class mitochondria-based pharmaceutical product that has a large potential to treat various rare diseases and cancer.
MitoTherapy Products are novel medicinal products using mitochondria isolated from human stem cells or human blood. Mitochondria are unique organelles that are responsible for energy production in cells. Based on our experimental results, mitochondria have a high potential to treat inflammatory diseases.
MitoTherapy Products are novel medicinal products using mitochondria isolated from human stem cells or human blood. Mitochondria are unique organelles that are responsible for energy production in cells. Based on our experimental results, mitochondria have a high potential to treat inflammatory diseases.
MitoTherapy Products are novel medicinal products using mitochondria isolated from human stem cells or human blood. Mitochondria are unique organelles that are responsible for energy production in cells. Based on our experimental results, mitochondria have a high potential to treat inflammatory diseases.
PAEAN’s Pipeline reflects our strategic focus on high-burden diseases with limited treatment options, progressing toward regulatory milestones with the support of national and global funding partners.
| Platform | Pipeline | Indication | Drug Discovery | Pre-Clinical | IND | Phase 1 | Phase 2 |
|---|---|---|---|---|---|---|---|
| Mitochondrial Transplantation (MitoTherapy Product) | PN-101 | PM/DM | |||||
| PN-RS | Parkinson Disease | ||||||
| PN-RS | Hearing Loss | ||||||
| PN-RS | Ophthalmic Disease | ||||||
| Modified Mitochondrial Transplantation (MitoCeutical Product) | PN-30X | Cancer, CNS Diseases | |||||
| Mitochondrial Augmentation Cell Therapy (Mitoaugmentation Product) | PN-20X | TBD | |||||
MILESTONE
Seoul National University Hospital
2018 UNTIL NOW
Korea Investment Partners with KRW 1.5 B
JUN 2018
Korea Investment Partners, Hana Ventures, Timefolio with KRW 6 B
JUN 2019
Korea Investment Partners, Hana Ventures Timefolio with KRW 4.5 B
JUN 2021
Jung-gu, Seoul
JUN 2021
World-first allogenic mitochondria as therapeutic agent
JUN 2021
MOU with Soonchunhyang University Medical Center and SIMS
SEP 2021 Until Now
Daol Investment, Hana Ventures, Timefolio, IMM Investment with KRW 7 B
SEP 2022
MOU with YiPSCELL
DEC 2022 Until Now
NCT04976140
JUN 2021 until JUN 2024
FEB 2025
PAEAN protects its innovations through a growing portfolio of patents, including granted and pending filings across Korea, the United States, and other major markets.
International Patent Applications
Korean Patents Granted
Total Global
Filings
We Collaborate with leading research institutions, hospitals, and global investors to Accelerate the Development of next-generation mitochondrial therapies.